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In order to extract the trend of contraction of vascular expansion, in the acquisition of the original video AVI images were converted frame sequence extracted from a focus of the study of vascular contours. In this paper, based on markers of vascular ultrasound frame watershed image segmentation method, the method for ultrasound image contrast is low, the characteristics of strong noise in the wavelet domain before marked increase. Experiments show that the method is more traditional region growing method to contour more accurately. The law is based on the blood vessels in the continuous-time cross-sectional area within the curve, more convenient and accurate pathological analysis of physicians. Thus, the method is more suitable for vascular ultrasound image boundary extraction.