This approach maps the colour distribution of an over/under stained image to that of a well stained target image. Reinhard presented a method for matching the colour distribution of an image to that of a target image by use of a linear transform in a perceptual colourspace (the lαβ colourspace of Ruderman et al. ) so as to match the means and standard deviations of each colour channel in the two images in that colourspace.

Reinhard_StainNormalization\Reinhard_code_explain.docx
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