Description: it is proposed an efficient approach for compression microarray images. It is utilized a hybrid wave Platform: |
Size: 3072 |
Author:邓宸伟 |
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Description: 从因子分析的角度出发解决基因表达谱分析问题。为解决独立成分分析方法在求解过程中的不稳定性,提出一种基于选择性独立成分分析的DNA微阵列数据集成分类器。首先对基因表达水平的重构误差进行分析,选择部分重构误差较小的独立成分进行样本重构,然后基于重构后的样本同时训练多个支持向量机基分类器,最后选择部分分类正确率较高的基分类器进行最大投票以得到最终结果。在3个常用测试集上验证了本文设计方法的有效性。-This paper tries to deal with gene expression problem in view of factor analysis. In order to overcome the instability problem caused by performing independent component analysis, a DNA microarray data ensemble classifier based on selective independent component analysis is proposed. The reconstruction error of each gene is analyzed firstly and a part of independent components which contribute relatively small reconstruction errors are selected to reconstruct new samples. After that, several support vector machine base classifiers are trained simultaneously. Finally, the best base classifiers with high correct rates are selected to participate in the ensemble, using the majority voting method. Results on three publicly available microarray datasets show the feasibility and validity of the method proposed in this paper. Platform: |
Size: 1427456 |
Author:cumtgyy |
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Description: Performs hierarchical clustering of data using specified method and
seraches for optimal cutoff empoying VIF criterion suggested in "Okada Y. et al - Detection of Cluster Boundary in Microarray Data by Reference to MIPS Functional Catalogue Database (2001)".
Namely, it searches cutoff where groups are independent. The techinque uses an econometric approach of verifying that variables in
multiple regression are linearly independent: if all the diagonal
elements of inverse correlation matrix of data are less than VIF-Performs hierarchical clustering of data using specified method and
seraches for optimal cutoff empoying VIF criterion suggested in "Okada Y. et al- Detection of Cluster Boundary in Microarray Data by Reference to MIPS Functional Catalogue Database (2001)".
Namely, it searches cutoff where groups are independent. The techinque uses an econometric approach of verifying that variables in
multiple regression are linearly independent: if all the diagonal
elements of inverse correlation matrix of data are less than VIF Platform: |
Size: 2048 |
Author:tra ba huy |
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Description: 为用户提供了一个开放的、可扩展的环境,用于在药品研究、遗传工程和其他与基因组、蛋白质等相关的项目中进行原型算法的开发以及应用。-Bioinformatics Toolbox™ offers computational molecular biologists and other research scientists an open and extensible environment in which to explore ideas, prototype new algorithms, and build applications in drug research, genetic engineering, and other genomics and proteomics projects. This bioinformatics software provides access to genomic and proteomic data formats, analysis techniques, and specialized visualizations for genomic and proteomic sequence and microarray analysis. Most Bioinformatics Toolbox functions are implemented in the open MATLAB® language, enabling you to customize the algorithms or develop your own. Platform: |
Size: 53026816 |
Author:zhangyuan |
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Description: RNA 和 DNA序列模拟 基因建模 数值模拟 采用matlab 编写 能计算几千个 基因点的特性和行为-In one type of gene expression analysis, fluorescently tagged messenger RNA from different cells are hybridized to a microscopic array of thousands of complimentary DNA spots that correspond to different genes. Illuminated spots emit different color light, indicating which genes are expressed (e.g., green=control, red=sample, yellow=both).
In this case study, MATLAB, the Image Processing and Signal Processing toolboxes were used to determine the green intensities from a small portion of a microarray image containing 4,800 spots. A 10x10 pattern of spots was detected by averaging rows and columns to produce horizontal and vertical profiles. Periodicity was determined automatically by autocorrelation and used to form an optimal length filter for morphological background removal. A rectangular grid of bounding boxes was defined. Each spot was individually addressed and segmented by thresholding to form a mask. The mask was used to isolate each spot from surrounding background. Individu Platform: |
Size: 4450304 |
Author:Tu Shu |
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Description: malab用于基因芯片数据的聚类研究和基因功能的研究-malab for microarray data clustering research and the study of gene function Platform: |
Size: 1024 |
Author:adolph |
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